$359.00
Description
Synvisc® One is a sterile, prefilled syringe intended for intra-articular administration in the knee. This hyaluronic acid-based viscosupplement supports joint lubrication and cushioning within established osteoarthritis protocols. Clinics stock it to streamline single-visit scheduling and maintain predictable procedure workflows, backed by US distribution.
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What Synvisc One Is and How It Works
Synvisc® One is a single-injection viscosupplement designed for intra-articular use by trained clinicians. The preparation contains a high-viscosity hyaluronic acid derivative that augments synovial fluid’s lubricating and shock-absorbing properties. In professional care pathways, it can be integrated into knee osteoarthritis management to support mobility-focused plans without adding compounding or reconstitution steps.
This product arrives as a ready-to-use, single-dose unit. The prefilled format reduces preparation time at the point of care and supports consistent technique. For broader category context, review our Orthopedic Injections.
Professional Applications
Orthopedic, sports medicine, PM&R, and rheumatology services commonly incorporate this single-visit HA option into their injection schedules. Teams may use it for new starts or for patients transitioning from multi-visit series, aligning procedure timing with imaging, bracing, or therapy appointments as needed. As a Hylan G-F 20 injection, it fits established viscosupplementation protocols and supports standardized documentation, consent, and follow-up practices within clinic pathways.
Care pathways often coordinate pre-procedure evaluation, sterile prep, and post-visit guidance in one visit. For comparative overviews, see our article Product Comparison.
Key Features
- Single-injection format: consolidates the course into one clinic visit
- Ready-to-use unit: reduces prep time and variability
- Hylan G-F 20 prefilled syringe: high-viscosity HA derivative
- Sterile, single-use device: supports aseptic technique
- Clear labeling: supports traceability in EMR and inventory logs
- Packaged with instructions for use: simplifies staff onboarding
Benefits in Practice
- Efficient scheduling: one visit simplifies calendars and chair time
- Workflow fit: prefilled unit integrates with standard injection kits
- Inventory clarity: unit-of-use simplifies order quantities and reorders
- Training consistency: straightforward product handling supports uniform technique
- Patient flow: single encounter can reduce rescheduling risk for multi-visit series
- Formulary standardization: Synvisc One viscosupplement supports consistent product use across providers
- Expected local reactions: clinics counsel on possible redness, itching, swelling, or bruising at the injection site
Composition & Ingredients
This preparation delivers a crosslinked hyaluronic acid derivative (hylan) in a sterile, aqueous medium for intra-articular administration. It is classified within the Hylan G-F 20 knee injection category used in viscosupplementation pathways. Excipients are typical for HA solutions and are detailed on the product label and package insert.
- Active component: hyaluronic acid derivative (hylan)
- Form: clear, sterile, prefilled single-dose syringe
- Vehicle: sterile aqueous solution; refer to the package insert for full listing
Packaging & Supply
The unit is supplied as a single-dose, prefilled syringe intended for one knee. The Synvisc One 6 mL syringe presentation supports standard intra-articular technique and eliminates vial draw-up. When shown on the label, concentration is 8 mg/mL with a 6 mL fill volume. The outer carton includes instructions for use. Lot number and expiration are displayed for traceability. SKU: 81517.
Clinics that prefer a multi-visit regimen can also review the course-based alternative, Classic 3 x 2 mL, within the same product family.
Ordering & Logistics
Create or verify your account to access contract and volume tiers. Sign in to request quotes, enable purchasing, and view shipment options aligned to clinic schedules. We provide temperature-controlled handling when required and tracked US delivery.
For interdisciplinary teams, align reorders with rheumatology or orthopedics calendars via the Rheumatology category view. For program design and cadence planning, see our article Timing and Frequency.
Comparable Products
Within the same class, clinics may also utilize the course-based alternative mentioned above for three-visit protocols. Explore broader HA options in Orthopedic Injections and review comparative insights in Durolane Comparison as you align product selection with your injection pathways.
Pricing & Access
Sign in to view live pricing. Eligible facilities can request volume-based tiers and contract pricing aligned to purchasing frequency. Your account manager can assist with formularies, clinic-specific preferences, and replenishment planning across locations.
Availability & Substitutions
Supply can vary by lot and distributor. If a substitution is required, confirm equivalency, handling, and scheduling impact with your clinical lead before switching. When replacing a Synvisc One knee injection with another HA option, verify the protocol (single-visit versus series), syringe volume, and any device compatibility needs. For additional perspective, see Gel Injections Guide.
Authoritative Sources
- Manufacturer Product Information
- FDA: Viscosupplementation Overview
- Arthritis Foundation: Viscosupplementation
Ready to add this single-dose HA option to your workflow? Sign in to confirm eligibility and schedule your next shipment.
Frequently Asked Questions
How does this single-dose HA product fit into clinic workflows?
It supports a one-visit injection plan for knee osteoarthritis pathways, reducing the need to coordinate multiple return appointments. Clinics often schedule imaging review, consent, and administration in a single encounter to simplify staffing and room utilization. The prefilled syringe format minimizes prep steps, allowing teams to focus on sterile technique and post-visit guidance. Coordinating follow-up calls or visits remains important for monitoring tolerance and reinforcing activity recommendations.
What supplies are typically used during administration?
Standard intra-articular injection supplies are used per your protocol. Teams typically prepare antiseptic solution, sterile gloves, drape, local anesthetic if indicated, appropriate gauge needle and syringe accessories, and a bandage. Ultrasound guidance may be used according to provider preference. The prefilled design reduces draw-up steps, but aseptic handling and verification of the lot and expiration are still required before use.
What should clinics communicate after the visit?
Advise recipients about routine post-injection expectations and when to contact the clinic. Mild, transient local reactions can include redness, itching, swelling, or bruising at the injection site. Encourage rest and activity modification per your protocol. Document the knee injected, technique, lot, expiration, and any immediate reactions. Set reminders for follow-up calls or visits, and coordinate with physical therapy or bracing teams as appropriate.
How should we plan inventory for single-dose viscosupplements?
Many clinics align inventory with weekly injection blocks. Keep safety stock that matches your average procedure volume and lead times. Track lot and expiration to prioritize near-dated units. The unit-of-use format supports straightforward reorders and charge capture. If your service line includes both single-dose and series-based HA options, separate bins and clear labeling reduce selection errors and help maintain consistent workflows across providers.
Are there storage or handling considerations?
Follow the product label for storage conditions and handling instructions. Many HA viscosupplements are stored at controlled room temperature, but you should confirm requirements for each lot and unit. Avoid freezing or excessive heat, and maintain sterility at all times. Check the package insert for any transport guidance and ensure your clinic’s procedures cover receipt, logging, and secure storage before use.
Can it be used alongside physical therapy or bracing programs?
Yes, many clinics coordinate injection visits with ongoing non-pharmacologic interventions such as physical therapy, home exercise plans, and bracing. Aligning these services can help maintain continuity of care and simplify scheduling. Ensure your care plan documents the injection date, concurrent therapies, and planned follow-up. Adjust activity recommendations based on clinical response and provider assessment at subsequent visits.
What adverse effects should staff anticipate and document?
Expected local reactions may include temporary pain, redness, itching, swelling, or bruising at the injection site. Advise recipients to report persistent or worsening symptoms. Follow your protocol for evaluating post-injection complaints and document findings, including onset, duration, and any interventions. Record the lot, expiration, and injection details in the EMR to support traceability and quality tracking within your musculoskeletal service line.
Specifications
- Main Ingredient: Hyaluronic Acid
- Manufacturer: SANOFI-AVENTIS U.S. LLC
- Drug Class: Orthopedic
- Generic Name: Hyaluronic Acid
- Package Contents: 6 mL x 1 Pre-Filled Syringe
- Storage Requirements: Room Temperature (2℃~25℃)
- Main Usage:
About the Brand
Synvisc
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