Synvisc® Classic Viscosupplement for Clinics

What Synvisc Classic Is and How It Works

Synvisc® Classic is a sterile, intra-articular viscosupplement supplied as hylan G-F 20 for use in the knee. Clinics integrate this line into nonoperative osteoarthritis pathways and image-guided injection services. We maintain US distribution to support reliable replenishment for licensed facilities.

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This preparation contains cross-linked hyaluronan designed to supplement the viscoelastic properties of synovial fluid. By augmenting fluid rheology, the solution may help reduce mechanical friction within the joint space and support smoother knee motion during daily activities. The class is frequently selected when clinicians seek a device-based option within multimodal care plans.

Administration is intra-articular and performed by qualified professionals using strict aseptic technique. Programs often incorporate ultrasound or fluoroscopic guidance according to local practice standards. For clinical context and evidence summaries, see Research Overview, and explore category options under Orthopedic Injections.

Professional Applications

Orthopedics, sports medicine, and rheumatology services use this viscosupplement as part of stepwise knee osteoarthritis management. A Hylan G-F 20 injection can be scheduled alongside physical therapy, bracing, and activity modification plans. It is suitable for inclusion in outpatient procedure blocks and can align with image-guided injection workflows when indicated.

Patient selection is essential. Avoid intra-articular administration in the presence of active joint or skin infection. Screen for known hypersensitivity to avian proteins. Transient local reactions, such as swelling or discomfort at the injection site, can occur and are generally managed with supportive measures.

Post-procedure guidance may include brief limitation of high-impact activities per clinic protocol. For broader background on class use within musculoskeletal care, review Knee Gel Injections.

Key Features

• Cross-linked hyaluronan base: designed to supplement synovial viscosity.
• Intra-articular use: suitable for knee joint injection by trained clinicians.
• Sterile, single-use design: supports aseptic technique and procedural efficiency.
• Hylan GF-20 prefilled syringe format: streamlined preparation and administration.
• Predictable rheology: consistent gel characteristics support reproducible technique.
• Clear labeling: supports lot and expiry tracking within inventory systems.
• Professional-grade presentation: packaged for clinical settings and procedure rooms.

Benefits in Practice

This product fits well into busy orthopedic and sports medicine schedules. Prefilled syringes reduce setup steps and minimize variability at the point of care. The consistent gel profile supports reproducible technique across clinicians and locations. Teams can standardize equipment, draping, and workflow to help maintain schedule integrity.

Synvisc Classic prefilled syringe 2 mL supports predictable chair time, which can simplify block scheduling and resource planning. The format adapts to ultrasound-guided or landmark-based approaches, depending on clinic preference. Staff can prepare rooms efficiently and focus on patient positioning, guidance, and documentation.

For additional perspective on the class, review Orthovisc Overview and a side-by-side article at Comparison Guide. Facilities can also browse ancillary supplies under Medical Devices to align procedure trays with local protocols.

Composition & Ingredients

Active component: hylan G-F 20, a cross-linked derivative of hyaluronan formulated for intra-articular use. The gel is supplied in a sterile, buffered aqueous vehicle appropriate for joint injection. As the line is derived from avian sources, assess for avian protein hypersensitivity during intake and consent processes.

This Hylan G-F 20 knee injection is intended for single-joint administration in a controlled clinical environment. Use established aseptic technique and standard precautions. Do not inject in the presence of local infection or severe inflammation at the intended site. Observe patients for immediate post-procedure tolerability and provide routine follow-up consistent with clinic policy.

Packaging & Supply

Each carton contains three prefilled syringes for clinical use. Each syringe provides 2 mL. The formulation corresponds to Synvisc Classic 16 mg/2 mL. Item SKU: 82248. Carton and unit labels display product identity, lot number, and expiration to facilitate receiving, recording, and rotation.

Units are intended for single use. Inspect primary packaging prior to procedure setup; do not use if the sterile barrier is compromised. Store and handle as directed on the manufacturer label and in accordance with facility policies. Rheumatology and orthopedic services can coordinate stocking through Rheumatology inventory pathways where applicable.

Ordering & Logistics

Create or sign in to a verified business account to view available contract tiers and manage procurement. Qualified organizations can enable volume allocations and approval workflows. Your team can save this SKU to lists for quick reorders, assign purchasing roles, and coordinate delivery schedules with case loads.

Our order desk supports routine, standing, and just-in-time requests. Shipment confirmations and status updates are shared promptly so coordinators can plan procedure days with confidence. Packaging is configured to protect sterile contents during transit. Documentation accompanying each shipment supports lot traceability and receiving checks.

Comparable Products

Clinics seeking a single-injection alternative within the same class often evaluate Synvisc One. For broader category exploration and to compare viscosupplements by injection schedule, material characteristics, and presentation, see Orthopedic Injections.

Pricing & Access

Sign in to view current clinic pricing and eligibility for volume or contract tiers. Approved accounts may submit purchase orders and align fulfillment with internal purchasing cycles. If your facility operates multiple locations, centralized ordering and site-level delivery preferences can be configured by your account manager.

Availability & Substitutions

Supply levels can vary based on manufacturer production and regional demand. Confirm needs early when planning injection series or multi-provider clinics. If a substitution is required, our team will recommend alternatives aligned with your protocols and formulary criteria, and will confirm product differences before fulfillment. No restock timing is promised until allocations are confirmed.

Authoritative Sources

• Manufacturer product information for hylan G-F 20 (professional labeling and indications).
• FDA resources on intra-articular hyaluronan devices for knee osteoarthritis.
• Professional society overviews, such as AAOS guidance on viscosupplementation in knee care.

Sign in to reserve clinic supply with temperature-controlled handling when required and tracked US delivery.