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ORTHOVISC® Knee Injections: Pain Relief & Improved Mobility

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Medically Reviewed

Profile image of Lalaine Cheng

Medically Reviewed By Lalaine ChengA dedicated medical practitioner with a Master’s degree in Public Health, specializing in epidemiology with a profound focus on overall wellness and health, brings a unique blend of clinical expertise and research acumen to the forefront of healthcare. As a researcher deeply involved in clinical trials, I ensure that every new medication or product satisfies the highest safety standards, giving you peace of mind, individuals and healthcare providers alike. Currently pursuing a Ph.D. in Biology, my commitment to advancing medical science and improving patient outcomes is unwavering.

Profile image of Lalaine Cheng

Written by Lalaine ChengA dedicated medical practitioner with a Master’s degree in Public Health, specializing in epidemiology with a profound focus on overall wellness and health, brings a unique blend of clinical expertise and research acumen to the forefront of healthcare. As a researcher deeply involved in clinical trials, I ensure that every new medication or product satisfies the highest safety standards, giving you peace of mind, individuals and healthcare providers alike. Currently pursuing a Ph.D. in Biology, my commitment to advancing medical science and improving patient outcomes is unwavering. on February 28, 2025

Orthovisc Knee Injections

Knee osteoarthritis is a common condition affecting aging populations, athletes, and individuals recovering from joint injuries. As cartilage deteriorates, patients experience stiffness, inflammation, and chronic pain, reducing mobility and quality of life. Orthovisc knee injections provide healthcare providers with a clinically proven, non-surgical solution to manage osteoarthritis symptoms effectively. Offering a safe and long-lasting viscosupplementation treatment, Orthovisc enables orthopedic specialists, pain management clinics, and rehabilitation centers to enhance patient care while reducing reliance on invasive procedures.

This viscosupplementation therapy relieves patients experiencing knee osteoarthritis by restoring lubrication and cushioning within the joint. Orthovisc injections for knee pain offer an alternative for individuals who do not respond well to oral medications or want to delay surgical interventions such as total knee replacement.

Medical practitioners must understand how Orthovisc works, its benefits, potential side effects, and patient selection criteria to ensure optimal treatment outcomes. This article explores what is Orthovisc for knee injections, their clinical efficacy, and their role in osteoarthritis management.

How Orthovisc Knee Injections Work

Orthovisc is a high-molecular-weight hyaluronic acid (HA) injection designed to supplement synovial fluid in the knee joint. Hyaluronic acid is a naturally occurring substance in the joint fluid that provides lubrication and shock absorption, reducing friction, and minimizing wear on cartilage. The body produces less hyaluronic acid as osteoarthritis progresses, leading to joint stiffness and pain. Orthovisc injections for knee osteoarthritis work by:

  • Restoring joint lubrication, reducing friction between bones
  • Enhancing shock absorption, preventing further cartilage breakdown
  • Improving joint mobility, allowing patients to move with less discomfort
  • Reducing inflammation, leading to long-term pain relief

Orthovisc is administered directly into the knee joint as a series of injections, typically over three to four weeks. The effects can last for up to six months, offering extended pain relief for patients with moderate to severe osteoarthritis.

Who Can Benefit from Orthovisc Injections for Osteoarthritis?

Orthovisc knee injections are suitable for patients experiencing knee osteoarthritis-related pain and mobility issues. Ideal candidates include:

  • Patients with moderate to severe osteoarthritis who have not responded well to NSAIDs or corticosteroids
  • Individuals looking for non-surgical treatment alternatives before considering knee replacement
  • Athletes and active individuals who want to maintain mobility and reduce joint pain
  • Patients who cannot tolerate oral pain medications due to gastrointestinal or cardiovascular concerns

While Orthovisc injections offer significant pain relief, they are not a permanent cure for osteoarthritis. Patients must maintain a healthy weight, exercise regularly, and follow a joint-friendly lifestyle to maximize treatment benefits.

What to Expect During an Orthovisc Injection Procedure

Administering Orthovisc knee injections is a minimally invasive, in-office procedure that requires no downtime. Consider the following: 

Pre-Treatment Preparation

  • The affected knee is cleaned and sterilized to prevent infection.
  • If necessary, excess fluid may be removed from the joint before injection.

Injection Process

  • A fine-gauge needle is used to inject Orthovisc directly into the knee joint.
  • Patients may feel slight pressure or mild discomfort during the injection.
  • The entire procedure takes approximately 10-15 minutes.

Post-Injection Care

  • Patients should avoid strenuous activities for 24-48 hours post-injection.
  • Mild swelling or soreness may occur but usually resolves within a few days.
  • The full benefits of the injection may take several weeks to develop.

Orthovisc injections can be repeated every six months to a year, depending on the patient’s response and severity of symptoms.

Clinical Efficacy of Orthovisc Knee Injections

Numerous clinical studies have demonstrated the effectiveness of Orthovisc injections for osteoarthritis. Research findings indicate:

  • Patients report significant reductions in pain and stiffness within four weeks of treatment.
  • Many individuals experience up to six months of relief, reducing their reliance on oral pain medications.
  • Compared to corticosteroid injections, hyaluronic acid therapy provides longer-lasting symptom relief without the risks of cartilage degradation.

Medical practitioners should consider Orthovisc injections as part of a multimodal osteoarthritis management plan, including physical therapy, weight management, and lifestyle modifications.

Potential Side Effects of this Injection

While generally well-tolerated, healthcare providers should be aware of possible side effects of Orthovisc knee injections:

  • Mild pain or swelling at the injection site
  • Temporary joint stiffness
  • Redness or warmth around the knee joint
  • Rare allergic reactions (especially in patients sensitive to avian-derived products)

Serious side effects are rare, but practitioners should educate patients on post-injection care and when to seek medical attention for unusual symptoms such as severe swelling, persistent pain, or signs of infection.

Where to Buy This medication for Your Practice

For healthcare providers looking to buy Orthovisc, sourcing from a trusted medical supplier ensures:

  • Authentic, FDA-approved Orthovisc injections
  • Competitive pricing for bulk orders
  • Reliable distribution with fast shipping

Ordering from licensed distributors guarantees practitioners receive high-quality products for safe and effective patient care.

Conclusion

Orthovisc knee injections provide an effective, non-surgical solution for patients suffering from osteoarthritis-related knee pain. Orthovisc improves mobility, reduces discomfort, and enhances overall quality of life by restoring joint lubrication and shock absorption. For medical practitioners, understanding the mechanism of action, patient selection criteria, and clinical efficacy of Orthovisc is essential for maximizing treatment success. As the demand for non-invasive osteoarthritis treatments grows, integrating Orthovisc injections into your practice can offer patients long-term pain relief and improved joint function.

Frequently Asked Questions (FAQs)

How does Orthovisc for knee injections work?

Orthovisc is a viscosupplementation therapy that involves injecting high molecular weight hyaluronic acid directly into the knee joint. In osteoarthritis, the natural hyaluronic acid in the synovial fluid diminishes, leading to increased friction, pain, and reduced mobility. By supplementing this lost hyaluronic acid, Orthovisc enhances the viscoelastic properties of the synovial fluid, providing better lubrication and shock absorption. 

How long do the injections for knee osteoarthritis last?

The therapeutic effects of Orthovisc injections can last up to six months, though the duration may vary depending on the severity of osteoarthritis and individual patient factors. Clinical studies have demonstrated significant pain relief and improved joint function lasting approximately 26 weeks following a standard regimen of three to four weekly injections. Factors such as activity level, weight management, and adherence to post-treatment care can influence the longevity of symptom relief.

Can Orthovisc be used alongside other osteoarthritis treatments?

Yes, Orthovisc can be effectively combined with other osteoarthritis management strategies. Integrating Orthovisc injections with physical therapy, weight management, and low-impact exercises can enhance overall treatment outcomes. This multimodal approach addresses various aspects of osteoarthritis, potentially leading to improved pain relief, increased joint function, and a better quality of life for patients. 

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