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BioPlus Co., Ltd.

40 mg1 mL x 2 Pre-Filled SyringesRx requiredIn stock

Order Nucleofill™ Medium Plus for Clinics

Non-Cross-Linked Hyaluronic Acid

Free shipping on orders over $800

5% off your first order, applied at checkout

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Storage
Room Temperature (2℃~25℃)
  • Ships within 24–48 hours

    Delivery typically 48–72 hours after shipping, up to 5–7 business days depending on origin and customs. Tracking is emailed when your order ships.

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    Send us photos or a video. We investigate and arrange a replacement where needed.

  • Licence checks

    Licences are checked against the state board and the NPI registry.

  • 100% genuine products

    In original manufacturer packaging, with lot numbers for full traceability. Lot numbers are shown on your packing slip and invoice.

Rated 5/5 by our clinic customers

250 active clinics · Supplying clinics since 2013

“Everything has been easy from ordering to delivery. The prices are good, orders arrive quickly, and the customer service has been great. I would definitely order from MWS again.”
Alex B., NP
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Nucleofill™ Medium Plus

$129.00
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Specifications at a glance

Manufacturer
BioPlus Co., Ltd.
Generic name
Non-Cross-Linked Hyaluronic Acid
Size / strength
40 mg
Package content
1 mL x 2 Pre-Filled Syringes
Main ingredient
Hyaluronic Acid And Lidocaine
Drug class
Cosmetic Injectable
Drug type
Hyaluronic Acid-Based Dermal Filler
Storage
Room Temperature (2℃~25℃)
Prescription
Rx required. Supplied to licensed practitioners only.

About Nucleofill™ Medium Plus

Nucleofill™ Medium Plus is an injectable hyaluronic acid dermal filler used by trained aesthetic providers for facial volumization and contour refinement. Licensed clinics and healthcare professionals can order Nucleofill™ Medium Plus online for professional treatment-room use, with sterile packaging and single-patient handling built into the workflow. The preparation includes lidocaine to support in-chair comfort during appropriately planned injection procedures.

Med Wholesale Supplies serves B2B aesthetic practices, med spas, and healthcare facilities that need authentic, brand-name professional-use injectable supplies through verified supply channels. This product fits clinics that require predictable handling, clear lot and expiry documentation, and US distribution for recurring aesthetic inventory planning.

Nucleofill™ Medium Plus Price and Clinic Ordering

Current prices and quantity breaks are shown on this page, and licensed clinics can order as a guest or with an account. Pricing may depend on account profile, volume tier, and current supply allocation, so the ordering portal is the best place to confirm the active rate before building a treatment-room restock. Clinics can add the item to saved purchasing lists, coordinate reorders across locations, and align order quantities with expected appointment volume.

When placing a Nucleofill Medium Plus order online, match the item displayed during checkout to your clinic protocol and internal purchasing controls. Review the product name, packaging condition, lot visibility, expiry date, and quantity before intake into inventory. For facilities managing multiple injectable lines, a consistent receiving process reduces documentation gaps and supports traceability from shelf to treatment room.

Quick tip: Assign one staff member to record lot and expiry details at receiving, before the unit is stored or staged for use.

What the Injectable Is and How It Works

This preparation is described as a non-cross-linked hyaluronic acid formulation with lidocaine. Hyaluronic acid is a naturally occurring glycosaminoglycan that binds water in soft tissue, helping add volume and support contour transitions when placed by a qualified injector. Lidocaine is a local anesthetic component that may improve procedural comfort without requiring a separate anesthetic injection step.

In professional use, the injector determines candidacy, facial mapping, tissue plane, injection depth, and volume according to training, anatomy, and the treatment objective. Nucleofill™ Medium Plus injectable use should remain within an aseptic clinical setting, with appropriate skin preparation, sharps handling, and post-procedure observation protocols. The product should not be presented as a self-administered cosmetic item or used outside trained professional practice.

Clinics evaluating the broader brand family can browse the Nucleofill range for related presentations and adjacent treatment planning. If your team distinguishes between skin quality support and structural contouring protocols, maintain separate protocol notes so staff do not substitute products by name alone.

Professional Applications in Aesthetic Practice

Nucleofill™ Medium Plus is used by clinics for facial contour refinement and support of moderate to deep folds when an injectable hyaluronic acid gel is appropriate. Common professional planning areas may include midface contour transitions, nasolabial folds, and marionette line softening, depending on the clinician’s assessment. The treatment plan should consider facial anatomy, prior procedures, skin condition, patient history, and the desired degree of projection or blending.

The product can sit within broader aesthetic workflows that also include resurfacing, regenerative procedures, or hydration-focused injectable care. Clinics that provide skin booster treatments often separate superficial skin-quality protocols from deeper contouring work so expectations, consent language, and follow-up timing remain clear. Teams offering mesotherapy supplies may also need distinct storage, treatment-area, and documentation pathways for each injectable category.

Questions such as whether Nucleofill “works” should be answered through clinician evaluation, product-appropriate technique, and realistic outcomes. Hyaluronic acid fillers can support volume and contour when used correctly, but results vary by tissue characteristics, injection plan, and aftercare. Practices should avoid promising a fixed duration or outcome when counseling candidates, because longevity and visible effect depend on the individual and the treated area.

Key Features for Clinic Workflow

  • Injectable hyaluronic acid formulation for professional facial volumization and contour refinement.
  • Integrated lidocaine supports patient comfort during in-office injection procedures.
  • Non-cross-linked hyaluronic acid composition supports hydration and soft-tissue contour.
  • Sterile, pre-filled syringe format supports efficient treatment-room preparation.
  • Single-patient use packaging helps maintain aseptic workflow and inventory accountability.
  • Sealed blister presentation protects the unit before opening for clinical use.
  • Lot and expiry visibility supports receiving records, traceability, and reorder planning.

These features matter most in busy aesthetic settings where treatment rooms turn over quickly and multiple injectors may use shared stock. A ready-to-use syringe reduces setup steps, while clear packaging helps staff rotate units by expiry and document use in the patient record. Consistent intake and storage procedures also help minimize preventable waste from damaged packaging or incomplete logs.

Composition and Ingredient Considerations

The preparation contains non-cross-linked hyaluronic acid and lidocaine. The hyaluronic acid component supports hydration and contour by binding water in the extracellular matrix, while lidocaine provides local anesthetic effect during injection. Clinics should refer to the manufacturer package insert for complete ingredient information, cautions, and handling instructions before adding the product to protocol.

Ingredient screening should be part of the consultation and consent workflow. Clinicians should assess prior filler exposure, history of hypersensitivity, active skin inflammation, planned dental or facial procedures, and any other factors that could alter risk. Because lidocaine is included, clinics should also account for known anesthetic sensitivities and cumulative anesthetic exposure across same-day procedures.

The term “skin booster” is sometimes used broadly in aesthetic discussions, but product choice should follow the actual formulation, injection depth, and treatment objective. If the goal is hydration-focused skin quality support rather than contouring, teams may consider related Nucleofill products such as Nucleofill Medium or Nucleofill Soft Plus when those presentations better match the protocol.

Packaging, Sterile Handling, and Storage Intake

Nucleofill Medium Plus is supplied as a sterile pre-filled syringe in a sealed blister pack. Each unit is intended for single-patient use by qualified professionals. The sealed presentation should remain intact until the procedure setup, and staff should not use units with compromised packaging, unclear labeling, or expired dating.

At receiving, inspect the outer packaging and record lot number, expiry, quantity, and storage location according to clinic policy. Use first-expiry, first-out rotation so older stock is used appropriately before newer units. Keep the product separated from look-alike injectable items to reduce selection errors, especially in practices carrying multiple HA gels, skin boosters, and biostimulatory products.

For logistics planning, we support temperature-controlled handling when required and tracked US delivery. Clinics should still follow the package insert and their internal standard operating procedures for storage conditions, receiving checks, and quarantine of any unit that arrives with damaged packaging or questionable integrity.

Safety, Side Effects, and Candidate Review

Dermal filler procedures can cause expected transient reactions, including localized redness, swelling, tenderness, bruising, itching, or firmness around injection sites. These effects are usually managed within the clinic’s post-procedure guidance, but severity, duration, or unusual presentation should prompt clinician assessment. Rare complications may include nodules, hypersensitivity reactions, infection, vascular compromise, tissue injury, or visual symptoms, which require urgent medical evaluation.

Candidate review should include medical history, allergies, prior filler treatments, current medications, immune or bleeding concerns, active infection, pregnancy or breastfeeding status when relevant to clinic policy, and any recent procedures in the treatment area. Anticoagulants, antiplatelet agents, and supplements that affect bleeding may increase bruising risk, so clinicians should evaluate them within the patient’s overall medical context rather than applying a generic rule.

Use anatomy-aware injection planning, aspirational safety practices where appropriate to technique, small controlled placements, and clear escalation protocols for suspected complications. The FDA notes that dermal fillers are medical devices with risks that depend on the product, user skill, injection site, and patient factors. Professional training, emergency supplies, and written adverse-event procedures are essential parts of responsible clinic use.

Documentation and Treatment-Room Controls

Good documentation links the specific unit to the patient record and the procedure performed. Record the product name, lot number, expiry date, treatment areas, injection technique notes, amount used according to your protocol, injector name, consent confirmation, and any immediate observations. If a unit is opened but not used, follow your clinic policy and the manufacturer instructions rather than returning it to general stock.

Practices with several injectors benefit from a shared product-preparation checklist. The checklist can include packaging inspection, room setup, skin preparation, sharps disposal, emergency protocol readiness, and post-procedure instructions. This structure helps keep Nucleofill Medium Plus treatment workflows consistent across providers while still allowing each clinician to individualize the injection plan.

Why it matters: Traceable records help clinics respond quickly if a product concern, adverse event, or inventory reconciliation issue arises.

How It Fits With Adjacent Aesthetic Services

Nucleofill™ Medium Plus may be used within a broader aesthetic menu when protocols are sequenced appropriately. Chemical peels, thread lifts, energy-based procedures, mesotherapy, PRP, and skin boosters all create different tissue effects and recovery timelines. Scheduling should account for inflammation, bruising risk, product placement, and the clinician’s preferred interval between procedures.

For teams refining injectable protocols, the article on mesotherapy clinical uses, risks, and workflow can help separate superficial multi-injection techniques from filler-based contouring. Clinics considering regenerative adjuncts may also find PRP therapy for skin regeneration useful when building staff education around procedure sequencing and patient counseling.

Internal training should define which services can occur on the same day, which require spacing, and which require senior injector approval. Clear sequencing reduces confusion at booking and helps front-desk teams avoid overpromising procedure combinations that need clinician review.

Related Nucleofill Choices and Alternatives

Practices that carry several products in the same brand family should select by protocol fit rather than by similar names. Nucleofill Strong 1.5 mL may be considered when the clinic’s treatment plan calls for that specific presentation, while Nucleofill 25 and Nucleofill 20 can be reviewed for separate protocol needs. Always align the exact product chosen with injector training, package insert directions, and treatment objectives.

The question “Is Nucleofill Strong a filler?” often reflects confusion between filler, skin booster, and biostimulatory terminology. In clinic communication, use the product’s actual composition and intended professional use rather than broad marketing categories. If a patient asks about duration, explain that visible results and retreatment timing vary by treatment area, technique, tissue response, and follow-up plan.

For additional brand-specific context, clinics can read about Nucleofill Medium and skin regeneration workflows or Nucleofill treatment planning. Use those materials for staff education support, not as a replacement for product labeling, hands-on training, or clinician judgment.

Authoritative Sources

Order Nucleofill™ Medium Plus through your clinic account to view current purchasing details, coordinate inventory, and support professional documentation from receiving through treatment-room use.

This content is for informational purposes only and is not a substitute for professional medical advice.

Questions clinics ask

Nucleofill™ Medium Plus is intended for licensed clinics, med spas, and healthcare professionals using professional aesthetic injectable protocols. Account verification and clinic ordering requirements may apply before purchase access is available.

The supplied product information describes Nucleofill™ Medium Plus as an injectable hyaluronic acid dermal filler with lidocaine for professional facial volumization and contour refinement. Clinics should classify and use it according to the package insert, injector training, and internal protocol.

Record the product name, lot number, expiry date, treatment area, injector, consent confirmation, and procedure notes in the patient record. Lot-level documentation helps support traceability and inventory reconciliation.

Common transient effects can include redness, swelling, tenderness, bruising, itching, or firmness at injection sites. Rare but serious complications may include hypersensitivity, nodules, infection, vascular compromise, tissue injury, or visual symptoms requiring urgent assessment.

Keep the sterile blister intact until procedure setup, inspect packaging before use, and follow the package insert and clinic storage procedures. Do not use units with compromised packaging, unclear labeling, or expired dating.

It may be incorporated into broader aesthetic workflows when procedures are appropriately sequenced by a qualified clinician. Timing should account for inflammation, bruising risk, injection areas, recovery needs, and the clinic’s written protocol.

MWS Customer Service Team

Ordering in volume or opening a clinic account? Talk to us.

Our customer service team helps you choose the right pack, label option and quantity for your clinic, and sets up your first order.

Monday to Friday, 9am to 6pm ET

Why clinics order from MWS

  • Built for licensed clinics

    Licences are checked against the state board and the NPI registry.

  • Every pack option named

    Each option names its dosage and pack size, so you know which pack you are ordering.

  • Volume pricing up front

    Quantity tiers are shown on the product, before you order.

  • Cold-chain packing

    Refrigerated lines ship in thermo-packaging with enough ice packs to hold temperature for up to 10 days.

“The customer care team was very efficient in offering hand-held guidance to choose the most cost-effective options.”
Dr Tukba Yalcin, Lumiere Aesthetics

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