What distinguishes this polynucleotide injectable from HA fillers?

Polynucleotide injectables are designed to support the dermal microenvironment by encouraging cellular activity and hydration, rather than adding immediate volume like hyaluronic acid gels. The material class is biostimulatory and may complement HA-based volumizing when combined thoughtfully under a licensed provider’s protocol. Many clinics use polynucleotides to condition skin quality, then layer HA or other modalities for contour changes. Selection should reflect individual goals, tissue characteristics, and technique training.

Who is permitted to administer this product?

Administration is restricted to qualified medical professionals working within their licensure and scope of practice. Clinicians should be trained in polynucleotide-based injection techniques and aseptic handling. Facilities should maintain protocols for patient selection, informed consent, and post-procedure guidance. Where applicable, supervision requirements and delegation policies must align with state regulations and institutional standards.

Where does it fit within combination protocols?

This class can be positioned before, between, or after other aesthetic steps depending on the program. Many clinics integrate it with neuromodulators, HA fillers, threads, or energy-based devices, spacing sessions to respect tissue recovery and provider preference. Croma PhilArt can serve as a skin-quality foundation, with volumizing or device work sequenced to achieve complementary effects. Always individualize timing and order based on anatomy and goals.

How should it be stored before use?

Store the unit at 2°C to 25°C, protected from light, and do not freeze. Keep it in its original packaging until the moment of use to preserve sterility and traceability. As with all injectables, follow clinic policies for temperature monitoring and inventory rotation. Discard any compromised or past-expiry items according to biohazard procedures and local regulations.

Which treatment areas are commonly selected?

Clinics frequently use polynucleotide injectables to support skin quality on the face, neck, and décolletage, and in select cases the hands. Specific patterns and depths reflect the provider’s training and the patient’s anatomical needs. Microinjection techniques can be adapted to target texture, tone, or elasticity goals within a broader aesthetic plan. Always follow clinic protocols and manufacturer guidance for area suitability.

How are treatment intervals planned in clinics?

Scheduling is tailored to clinic protocols and individual considerations. Many programs use a short series of sessions spaced several weeks apart, then transition to periodic maintenance, often in the three to six month range per provider discretion. Interval decisions should consider skin status, modality combinations, and recovery timing around other procedures. Avoid prescriptive one-size-fits-all schedules; use clinical judgment and patient objectives to set cadence.

Who may not be an appropriate candidate?

Do not use in the presence of active skin infections or in individuals with known hypersensitivity to polynucleotides. Exercise caution in autoimmune conditions or where injectable procedures are otherwise contraindicated. Pregnancy and lactation require clinical evaluation and alignment with clinic policy. As with any injectable, comprehensive history, examination, and informed consent are essential before treatment.

Croma® PhilArt

Croma® PhilArt Injectable for Clinics

Name: Wholesale Croma® PhilArt Injectable – Clinic Supply
SKU: 100051
Price: 105.99 USD
Availability: InStock

Skin Revitalizing Treatment

$105.99

Description

This purified polynucleotide injectable is designed for professional aesthetic practice. It supports skin quality protocols using fine-needle microinjections performed by licensed clinicians. Inventory planning is streamlined through US distribution.

Clinics stock this preparation to complement regenerative workflows and to maintain consistent portfolios across face, neck, and hand programs. The formulation is selected for its handling characteristics, multi-area versatility, and predictable integration with other modalities. Procurement teams value consistent sourcing and familiar technique requirements across sessions.

What Croma® PhilArt Is and How It Works

Croma® PhilArt is a highly purified polynucleotide-based injectable intended for use by qualified medical providers. It is delivered with fine needles into targeted tissue planes, where the polynucleotide matrix can support cellular activity and dermal hydration.

As a biostimulating preparation, it may encourage fibroblast function and extracellular matrix synthesis. Improvements develop gradually, helping clinics aim for subtle, natural-appearing changes aligned with professional aesthetic goals.

Med Wholesale Supplies serves licensed clinics and healthcare professionals with authentic, brand-name medical products sourced through vetted distributors.

This product fits mesotherapy-style workflows and can be used alone or alongside energy devices, hyaluronic acid fillers, or threads. For a concise background on this class, see Product Overview.

Professional Applications

Use this line to support baseline skin quality in the face, neck, and décolletage. It also fits hand-focused programs and localized texture refinement within a clinic’s aesthetic pathway. Protocols vary by technique, indication, and training.

Many teams list a Croma PhilArt aesthetic treatment within comprehensive skin conditioning menus, often as a standalone session or as part of staged plans around other procedures.

The preparation can be paired with category protocols such as Mesotherapy and Skin Boosters, and supported with appropriate cannulas or microinjection tools. For instrumentation, consider SoftFil Cannula or MicronJet according to your technique and training.

For additional formulations from the manufacturer, explore the Croma Brand portfolio available to licensed accounts.

Key Features

This Croma PhilArt dermal injectable offers the following attributes for professional settings:

Purified polynucleotide matrix: supports cellular activity and dermal hydration.
Biostimulatory action: encourages fibroblast function and extracellular matrix renewal.
Fine-needle delivery: suited to microdroplet, mesotherapy, or cannula-assisted placement.
Manufacturing standards: produced under European GMP and quality system oversight.
Clinic-oriented handling: smooth flow through small-gauge needles and predictable integration.
Non-invasive pathway: injectable approach avoids incisions and fits routine aesthetic sessions.
Portfolio fit: complements HA fillers, neuromodulators, threads, and energy-based devices.
Traceability support: lot and expiry labeling facilitates documentation.
Storage guidance: stable within the labeled room-temperature range; protect from light.

Benefits in Practice

Teams adopt this preparation for its workflow fit, not for claims of cure or treatment. The formulation’s handling and versatility help clinicians design efficient, reproducible sessions across a spectrum of skin quality goals.

PhilArt by Croma aligns with commonly used microinjection patterns, enabling flexible scheduling and straightforward operator control. It can be layered with complementary modalities while maintaining conservative, natural-appearing planning.

Flexible scheduling: integrates with staged or maintenance calendars.
Consistent handling: predictable flow supports precise placement.
Combination-friendly: pairs with device and injectable protocols.
Inventory efficiency: single-use unit simplifies stock rotation.

Composition & Ingredients

This injection centers on highly purified polynucleotides suspended in a sterile aqueous carrier suitable for injectable use.

Active component: polynucleotides in highly purified form.
Vehicle: sterile, buffered aqueous solution.

The formulation strategy focuses on biostimulation and hydration support through nucleic acid polymers rather than volumizing gel technology. Avoid mixing in the same syringe with other agents unless your institutional protocol documents compatibility and your medical director approves.

Packaging & Supply

Clinics often position this as a Croma PhilArt skin booster within their regenerative menus. Presentation is a sterile, single-use injectable unit suitable for professional administration.

Each unit is lot- and expiry-labeled to support traceability in your inventory system. Follow local protocols for sharps disposal and accountability after use. Internal reference: SKU 100051.

Administer only by qualified medical providers trained in polynucleotide-based techniques. Do not use on individuals with active skin infections, known hypersensitivity to polynucleotides, or conditions in which injectable aesthetic procedures are contraindicated. Evaluate autoimmune disorders, pregnancy, and lactation per clinic policy and clinical judgment.

Storage: 2°C to 25°C. Protect from light. Do not freeze. Maintain the unit in its original packaging until use, respecting the labeled shelf life.

Ordering & Logistics

Account verification is required for access. Sign in to view availability and request allocation under your clinic profile. Volume and contract tiers are available for qualified facilities.

Orders are fulfilled with temperature-controlled handling when required and tracked US delivery. Consolidate items on a single order to streamline receiving and documentation workflows.

Comparable Products

For adjacent options in the same class, consider Next Variant for higher-intensity programs or Nucleofill 2.5 as another polynucleotide-based selection. Match any substitute to your protocol and patient cohort.

Pricing & Access

Sign in to your account to view pricing and clinic-specific tiers. Contract purchasing and volume schedules can be arranged for eligible facilities through our team.

Availability & Substitutions

Supply can vary by demand and regulatory considerations. If a preferred presentation is unavailable, confirm acceptability of a substitute with your medical director and align it with existing protocols. Alternatives across the same class or from the broader Skin Boosters or Mesotherapy categories may be suitable after clinical review.

Authoritative Sources

Ready to add this line to your aesthetic portfolio? Sign in to request allocation for your facility today.

Frequently Asked Questions

What distinguishes this polynucleotide injectable from HA fillers?
Polynucleotide injectables are designed to support the dermal microenvironment by encouraging cellular activity and hydration, rather than adding immediate volume like hyaluronic acid gels. The material class is biostimulatory and may complement HA-based volumizing when combined thoughtfully under a licensed provider’s protocol. Many clinics use polynucleotides to condition skin quality, then layer HA or other modalities for contour changes. Selection should reflect individual goals, tissue characteristics, and technique training.
Who is permitted to administer this product?
Administration is restricted to qualified medical professionals working within their licensure and scope of practice. Clinicians should be trained in polynucleotide-based injection techniques and aseptic handling. Facilities should maintain protocols for patient selection, informed consent, and post-procedure guidance. Where applicable, supervision requirements and delegation policies must align with state regulations and institutional standards.
Where does it fit within combination protocols?
This class can be positioned before, between, or after other aesthetic steps depending on the program. Many clinics integrate it with neuromodulators, HA fillers, threads, or energy-based devices, spacing sessions to respect tissue recovery and provider preference. Croma PhilArt can serve as a skin-quality foundation, with volumizing or device work sequenced to achieve complementary effects. Always individualize timing and order based on anatomy and goals.
How should it be stored before use?
Store the unit at 2°C to 25°C, protected from light, and do not freeze. Keep it in its original packaging until the moment of use to preserve sterility and traceability. As with all injectables, follow clinic policies for temperature monitoring and inventory rotation. Discard any compromised or past-expiry items according to biohazard procedures and local regulations.
Which treatment areas are commonly selected?
Clinics frequently use polynucleotide injectables to support skin quality on the face, neck, and décolletage, and in select cases the hands. Specific patterns and depths reflect the provider’s training and the patient’s anatomical needs. Microinjection techniques can be adapted to target texture, tone, or elasticity goals within a broader aesthetic plan. Always follow clinic protocols and manufacturer guidance for area suitability.
How are treatment intervals planned in clinics?
Scheduling is tailored to clinic protocols and individual considerations. Many programs use a short series of sessions spaced several weeks apart, then transition to periodic maintenance, often in the three to six month range per provider discretion. Interval decisions should consider skin status, modality combinations, and recovery timing around other procedures. Avoid prescriptive one-size-fits-all schedules; use clinical judgment and patient objectives to set cadence.
Who may not be an appropriate candidate?
Do not use in the presence of active skin infections or in individuals with known hypersensitivity to polynucleotides. Exercise caution in autoimmune conditions or where injectable procedures are otherwise contraindicated. Pregnancy and lactation require clinical evaluation and alignment with clinic policy. As with any injectable, comprehensive history, examination, and informed consent are essential before treatment.

Specifications

Main Ingredient: Polynucleotides
Manufacturer: Croma Pharma
Drug Class: Skincare Product
Generic Name: Polynucleotides
Package Contents: 2mL x 1 Syringe
Storage Requirements: Room Temperature (2℃~25℃)
Main Usage: Scaring/ Fine Line Filler

About the Brand

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