$1,299.00
Description
Entyvio® is an intravenous biologic supplied for gastroenterology infusion programs. This listing provides the non-English packaged vial used in adult ulcerative colitis and Crohn’s care where advanced therapy is indicated. Clinics stock this preparation to maintain continuity for cross-border allocations and patient transitions after anti-TNF therapy, supported by US distribution.
What Entyvio Is and How It Works
This product is a gut-selective monoclonal antibody formulated for intravenous infusion in supervised settings. The active component is Vedolizumab, an α4β7 integrin antagonist that limits trafficking of lymphocytes to gastrointestinal tissue. Clinics use it within GI-directed infusion pathways to support treatment objectives defined by prescribers and institutional protocols.
Med Wholesale Supplies serves licensed clinics and healthcare professionals with authentic, brand-name medical products sourced through vetted distributors. The vial is intended for preparation and administration by trained teams following institutional standards and the approved label. Pharmacy and nursing staff typically coordinate verification, aseptic reconstitution, and infusion monitoring.
Infusion teams should maintain vigilance for neurologic or visual changes. Rare cases of progressive multifocal leukoencephalopathy have been reported with some immunomodulatory therapies; blurred vision, loss of vision, or new neurologic symptoms warrant immediate escalation. Coordinate patient counseling and monitoring per site policies, and document findings in the infusion record.
Professional Applications
GI practices, health-system infusion suites, and independent centers schedule this therapy within defined induction and maintenance pathways. It supports adults who have not responded adequately to conventional treatment or anti-TNF agents. Pharmacy services typically manage receipt, verification, aseptic reconstitution, and chair-time coordination for a Vedolizumab injection prepared for IV use. For adjacent categories and inventory planning across service lines, review our Pharmaceuticals.
Key Features
- Hospital-grade biologic: manufactured to stringent quality benchmarks.
- Single-use vial: sterile presentation for aseptic preparation.
- Vedolizumab 300 mg vial: concentrate prepared for IV infusion.
- GI-selective mechanism: targets α4β7 integrin pathways.
- Non-English packaging: suitable where labeling language flexibility is permitted.
- Lot and expiry: clear label visibility to support traceability.
- Center workflow fit: integrates with standard infusion protocols and documentation.
Benefits in Practice
This preparation supports standardized workflows across gastroenterology infusion programs. Pharmacy can align ordering and receipt with planned chair utilization, while nurses follow consistent steps for reconstitution, verification, and observation. Predictable handling steps help reduce variability and streamline training for new staff.
The product’s GI-selective mechanism supports prescribers who favor organ-targeted approaches within the broader biologics landscape. Teams can integrate it into existing induction and maintenance calendars without redesigning scheduling templates. Clear lot and expiry labeling aids charge capture and traceability in electronic systems. Inventory managers can align reorders with forecasted maintenance cycles to limit rush restocks and avoid excessive on-hand quantities.
Composition & Ingredients
Active ingredient: Vedolizumab biologic (integrin antagonist) supplied as a monoclonal antibody for intravenous use.
Inactive components: Manufacturer-specific excipients vary by market. Refer to the supplied package leaflet and local institutional references for full excipient information. Because this is a non-English pack, ensure your team has access to an English-language reference text or digital labeling resource during receipt and preparation.
Packaging & Supply
Pack configuration: 300 mg x 1 vial. This listing reflects non-English packaging. Packaging language, leaflet, and outer carton may differ from US retail presentation. The vial, batch number, and expiry date display on the label for routine verification and documentation.
SKU: 89544. Verify item and lot details at check-in and record into your inventory platform prior to assignment to a patient visit. Store and handle according to the manufacturer’s label and your facility’s aseptic preparation policies.
Ordering & Logistics
Account verification is required. Sign in to view volume and contract pricing tiers available to licensed facilities. You can submit purchase orders through your account portal or request a quote for coordinated scheduling with your infusion calendar. If your practice uses centralized receiving, assign a designated contact for delivery confirmation and reconciliation.
Provide your clinic license and any procurement preferences during onboarding to streamline future reorders. For purchasing workflow tips and supply chain setup, see our internal reference article, Wholesale Guide. Contact your representative for pack availability or to discuss aligned allocations across multiple sites.
Comparable Products
Clinics often evaluate alternatives within the IBD biologics class when building formularies or substitution plans. Programs focused on Entyvio for Crohn’s disease may also consider anti-TNF or other immune-pathway agents based on prescriber preference and payer guidance. For reference, compare these lines from our catalog: Anti-TNF Option, PEGylated Option, IL-6 Pathway, and CD20 Therapy. For background reading on class considerations, review Remicade Overview.
Pricing & Access
Sign in to view pricing. Volume and contract tiers are available for qualified accounts, including multi-site practices and hospital-affiliated clinics. Your representative can align quotes with forecasted start dates and maintenance calendars. Formal proposals can include anticipated allocation windows, alternate pack options when relevant, and documentation required by your purchasing department.
Availability & Substitutions
Stock may vary by lot and pack language. If your clinic requires a substitution, confirm with the prescriber and pharmacy before adjusting schedules. Brief supply gaps can occur during market transitions or allocation changes; maintain a short buffer aligned to your average weekly usage. When reviewing formulary choices for Entyvio for ulcerative colitis, coordinate with your P&T leadership to ensure continuity protocols and patient communications are in place.
Authoritative Sources
For further reference on labeling, pharmacology, and safety, consult these resources. The manufacturer’s HCP portal and the FDA label provide primary documentation on preparation and administration. These sources also cover key details often discussed by clinicians when reviewing Entyvio mechanism of action and class positioning.
Ready to align supply with your infusion schedule? Sign in to request a quote and allocate stock with temperature-controlled handling when required and tracked US delivery.
Frequently Asked Questions
What format is supplied and how is it used in clinic?
This listing supplies a single-use vial intended for intravenous infusion in supervised settings. Pharmacy receives and verifies the lot, performs aseptic reconstitution per the label, and releases the dose to nursing for administration and observation. The product fits standard GI infusion workflows that include pre-infusion review, chair-time scheduling, vitals monitoring, and post-infusion documentation. Because the pack is non-English, ensure your team has access to an English-language reference or electronic labeling during receipt and preparation steps.
How should clinics manage non-English packaging?
At receiving, match the item to your purchase order and confirm lot and expiry on the label. Keep an English-language reference or electronic label available for verification and counseling. Update your inventory system with the SKU, lot, and expiration, and store the leaflet with the medication. If multiple languages circulate across your locations, standardize a quick-reference sheet to support technicians and nurses during compounding and chairside checks. Confirm your local policy permits non-English outer cartons before scheduling patients.
What are typical storage and handling considerations?
Follow the manufacturer’s label and your facility policies for storage, preparation, and administration. Maintain sterility during reconstitution and avoid unnecessary agitation. Use appropriate PPE, biological safety cabinets when required, and closed-system transfer devices according to your site standards. Document lot numbers, preparation times, and beyond-use timing per your institution’s procedures. Do not combine biologics in the same bag or line unless specifically directed by the prescriber and supported by compatibility data.
Which patient populations are commonly scheduled?
In many programs, adults with moderately to severely active ulcerative colitis or Crohn’s disease are scheduled when prescribers determine advanced therapy is indicated. Clinics may prioritize candidates who did not respond adequately to conventional therapy or anti-TNF agents, following established care pathways. Final patient selection, dosing strategy, and monitoring plans remain at the prescriber’s discretion and should align with labeling and institutional protocols.
What safety checks should infusion teams complete?
Before infusion, confirm the patient, order, lot, and expected monitoring plan. Screen for infections per protocol, and review recent lab or imaging results if required by your practice. During and after infusion, monitor vitals and patient-reported symptoms. Escalate promptly for allergic reactions, new neurologic changes, or visual symptoms. Progressive multifocal leukoencephalopathy is rare but serious; blurred vision, vision loss, or new neurologic deficits require immediate clinical evaluation and documentation.
Can clinics substitute alternatives if this item is constrained?
Substitution decisions belong to the prescriber and your P&T leadership. Some clinics consider alternatives in other classes, such as anti-TNF agents or molecules acting on different immune pathways, based on clinical context and payer requirements. Coordinate any switch with pharmacy, nursing, and scheduling to maintain continuity and minimize chair-time disruptions. Update patient education materials and verify benefit coverage before rescheduling maintenance visits.
How does this product integrate with billing and inventory systems?
At receipt, capture the SKU, lot, and expiry in your inventory platform. Many centers use bar-code scanning and automated charge capture once the dose is released to nursing. Align modifiers and internal charge codes with your revenue cycle policies. Retain documentation of preparation and administration in the patient record. If your system tracks waste or partial vials, ensure reconciliation fields are completed to support internal reporting and purchasing forecasts.
Specifications
- Main Ingredient:
- Manufacturer: Takeda
- Drug Class:
- Generic Name: Vedolizumab
- Package Contents: 300mg x 1 Vial
- Storage Requirements: Refrigerator (2°C-8°C)
- Main Usage:
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