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Radiesse Vs. Juvederm Voluma: A Comparison

Post written by admin on November 1, 2023

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radiesse vs juvederm Voluma

Are you concerned about wrinkles and facial volume loss but want to avoid surgery? Dermal fillers offer a non-surgical solution to rejuvenate your appearance. These treatments can effectively erase fine lines and restore lost facial volume by safely injecting biocompatible materials beneath your skin’s surface.

In this guide, we’ll inspect two popular dermal fillers: Radiesse and Juvederm Voluma. We’ll cover their unique features, ingredients, safety records, longevity, and costs so you can confidently decide which option is best for addressing your concerns and achieving a more youthful and radiant appearance.

A Closer Look at Radiesse and Juvederm Voluma

Radiesse and Juvederm Voluma are among the most popular and well-studied filler options available today. “They are both safe and effective for restoring volume and contour to the face. However, it’s important to choose a qualified and experienced practitioner, as technique and placement can greatly impact the results.” says Dr. Sarah Lee, Board-Certified Dermatologist.

Radiesse, developed by Merz Aesthetics, is a highly regarded dermal filler that plays a significant role in non-surgical rejuvenation. Its primary component, calcium hydroxylapatite microspheres, offers an innovative method for enhancing facial volume.

The primary active ingredient in Radiesse is calcium hydroxylapatite, which acts as a supportive structure beneath the skin’s surface. This framework not only provides immediate lift and volume but also stimulates collagen production. Collagen, the body’s natural regenerator, is crucial for maintaining a youthful appearance. Radiesse stands out among dermal fillers due to its blend of instant results and long-term collagen stimulation.

On the other hand, Juvederm Voluma, created by Allergan, is a premier dermal filler renowned for restoring facial volume and contour. Its key ingredient, hyaluronic acid, is a defining feature.

Juvederm Voluma’s brilliance lies in its formulation of hyaluronic acid, which acts as a hydration sponge beneath the skin, binding to water molecules and creating volume exactly where needed. This results in enhanced facial contours that remain youthful and lifted. The product is highly regarded for its immediate volume enhancement, making it an excellent choice for those seeking to restore cheek fullness or enhance jawline definition.

Key Differences Between Radiesse and Juvederm Voluma


Radiesse is primarily composed of calcium hydroxylapatite microspheres, providing immediate volume and lift while stimulating collagen production. On the other hand, Juvederm Voluma relies on hyaluronic acid, a natural substance in the body that acts as a hydration sponge under the skin, creating volume.

Intended Uses and Treatment Areas

We commonly choose Radiesse to address deep wrinkles and fine lines, such as marionette lines and nasolabial folds, as well as to restore volume in the hands. Juvederm Voluma excels in enhancing facial contours, with applications for cheek augmentation, jawline contouring, and addressing age-related mid-face volume loss. “In my experience, Radiesse and Juvederm Voluma are both excellent fillers for treating volume loss in the face. While Radiesse provides more structure and support, Juvederm Voluma is ideal for adding fullness to the cheeks and midface. Ultimately, the best choice depends on the individual patient’s aesthetic goals and anatomy.” says Dr. Amy Forman Taub, Board-Certified Dermatologist.

Duration of Results

Radiesse offers immediate results with continued improvement through collagen stimulation, often lasting up to a year or more. Juvederm Voluma provides rapid volume enhancement that can endure for up to two years, making it a preferred choice for those seeking longer-lasting results.

Efficacy and Clinical Trials


A pivotal study conducted across four U.S. medical centers demonstrated that Radiesse achieved an 82 percent improvement in treated nasolabial folds, while the control agent showed only 27 percent improvement. In the study, 79 percent of patients preferred Radiesse, which required nearly half the volume compared to the control agent. Both Radiesse and the control agent demonstrated safety and tolerance, with no severe adverse events reported.

Juvederm Voluma:

A study examined the efficacy of Juvederm Voluma XC, a hyaluronic acid filler, in addressing age-related midface volume deficit. Patient-reported outcomes over two years showed that 92.8% of patients reported improved cheek volume after six months, with 79.0% still reporting improvement at two years. Patients also noted increased satisfaction in various areas and appeared, on average, five years younger at six months and three years younger at two years. The treatment was well-tolerated, with minor adverse reactions lasting ≤2 weeks.

Safety and Side Effects

Both Radiesse and Juvederm Voluma are safe options, but we should keep specific considerations in mind:

Allergic Reactions: It is essential to undergo an allergy test before the procedure to ensure that you do not exhibit allergic reactions to the components of these fillers.

Provider Expertise: Choosing a certified and experienced practitioner is crucial to ensure proper injection techniques and a sterile environment during the procedure.

Common Side Effects: Both fillers can cause common side effects, such as bruising, swelling, redness, and tenderness at the injection site. Fortunately, these side effects are typically mild and subside within a few days to a week.

Special Considerations: While there is insufficient research on the safety of dermal fillers during pregnancy and breastfeeding, it is generally advisable to postpone such treatments until after these life phases.

Interactions and Medications: Inform your practitioner about any medications, supplements, or pre-existing medical conditions, as these can impact the safety and outcome of the procedure.

Follow-Up Care: Adhering to the recommended post-procedure care instructions is crucial for optimal results and safety.

Cost Comparison between Radiesse and Juvederm Voluma


The average cost of Radiesse ranges from $225.00 to $245.00 per syringe. The number of syringes required for treatment can vary based on the treatment area and the desired results. For example:

Nasolabial Folds: Typically, one to two syringes of Radiesse may be needed, with each syringe costing around $225.00 to $245.00.

Marionette Lines: Marionette lines may require one to two syringes, with each syringe costing around $225.00 to $245.00.

Hand Rejuvenation: Hand rejuvenation may require multiple syringes, depending on the extent of volume loss. Generally, two to three syringes may be needed, with each syringe costing around $225.00 to $245.00.

Juvederm Voluma:

The average cost of Juvederm Voluma ranges from $339.00 to $359.00 per syringe. Similar to Radiesse, the number of syringes required can vary based on the treatment area and desired results. For example:

Cheek Augmentation: Cheek augmentation with Juvederm Voluma may require one to two syringes, with each syringe costing around $339.00 to $359.00.

Jawline Contouring: Jawline contouring may require one to two syringes, with each syringe costing around $339.00 to $359.00.

Mid-Face Volume Loss: Restoring mid-face volume with Juvederm Voluma may require one to two syringes, with each syringe costing around $339.00 to $359.00.

It’s important to note that these are average prices and may vary depending on the location, the expertise of the provider, and any additional factors involved. Additionally, the number of syringes required can differ for each individual, based on their specific needs and goals.

Which Is Suitable For You?

When deciding between Radiesse and Juvederm Voluma to achieve your aesthetic objectives, a skilled practitioner plays a crucial role. Their expertise guides the selection of the most appropriate dermal filler, ensuring safe and precise execution. Whether addressing fine lines or revitalizing facial volume, you can most effectively achieve your desired enhancements under the guidance of experienced hands, ensuring both your safety and satisfaction.